AskDefine | Define rickets

Dictionary Definition

rickets n : childhood disease caused by deficiency of vitamin D and sunlight associated with impaired metabolism of calcium and phosphorus [syn: rachitis]

User Contributed Dictionary

English

Noun

rickets
  1. A disorder of infancy and early childhood caused by a deficiency of vitamin D, causing soft bones.

Translations

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Extensive Definition

Rickets is a softening of the bones in children potentially leading to fractures and deformity. Rickets is among the most frequent childhood diseases in many developing countries. The predominant cause is a vitamin D deficiency, but lack of adequate calcium in the diet may also lead to rickets. Although it can occur in adults, the majority of cases occur in children suffering from severe malnutrition, usually resulting from famine or starvation during the early stages of childhood. Osteomalacia is the term used to describe a similar condition occurring in adults, generally due to a deficiency of vitamin D. The origin of the word "rickets" is unknown. The Greek derived word "rachitis" (meaning "inflammation of the spine") was later adopted as the scientific term for rickets, due chiefly to the words' similarity in sound.

Epidemiology

Those at higher risk for developing rickets include:
  • Breast-fed infants whose mothers are not exposed to sunlight
  • Breast-fed infants who are not exposed to sunlight
  • Individuals not consuming fortified milk, such as those who are lactose intolerant
Individuals with red hair have been speculated to have a decreased risk for rickets due to their greater production of vitamin D in sunlight.

Etiology

Vitamin D is required for proper calcium absorption from the gut. In the absence of vitamin D, dietary calcium is not properly absorbed, resulting in hypocalcemia, leading to skeletal and dental deformities and neuromuscular symptoms, e.g. hyperexcitability.

Presentation

Signs and symptoms of rickets include:
An X-ray or radiograph of an advanced sufferer from rickets tends to present in a classic way: bow legs (outward curve of long bone of the legs) and a deformed chest. Changes in the skull also occur causing a distinctive "square headed" appearance. These deformities persist into adult life if not treated.
Long-term consequences include permanent bends or disfiguration of the long bones, and a curved back.

Diagnosis

A doctor may diagnose rickets by:

Treatment and prevention

The treatment and prevention of rickets is known as antirachitic.

Diet and sunlight

Treatment involves increasing dietary intake of calcium, phosphates and vitamin D. Exposure to ultraviolet light (sunshine), cod liver oil, halibut-liver oil, and viosterol are all sources of vitamin D.
A sufficient amount of ultraviolet in sunlight each day and adequate supplies of calcium and phosphorus in the diet can prevent rickets. Darker-skinned babies need to be exposed longer to the ultraviolet rays. The replacement of vitamin D has been proven to correct rickets using these methods of ultraviolet light therapy and medicine.
Recommendations are for 200 international units (IU) of vitamin D a day for infants and children. Children who do not get adequate amounts of vitamin D are at increased risk of rickets. Vitamin D is essential for allowing the body to uptake calcium for use in proper bone calcification and maintenance.

Supplementation

Sufficient vitamin D levels can also be achieved through dietary supplementation. Vitamin D3 (cholecalciferol) is the preferred form since it is more readily absorbed than vitamin D2. Most dermatologists recommend vitamin D supplementation as an alternative to unprotected ultraviolet exposure due to the increased risk of skin cancer associated with sun exposure.
According to the American Academy of Pediatrics (AAP), infants who are breast-fed may not get enough vitamin D from breast milk alone. For this reason, the AAP recommends that infants who are exclusively breast-fed receive daily supplements of vitamin D from age 2 months until they start drinking at least 17 ounces of vitamin D-fortified milk or formula a day. This requirement for supplemental vitamin D is not a defect in the evolution of human breastmilk but is instead a result of the modern-day infant's decreased exposure to sunlight.

References

rickets in Czech: Křivice
rickets in German: Rachitis
rickets in Spanish: Raquitismo
rickets in Finnish: Riisitauti
rickets in French: Rachitisme
rickets in Korean: 구루병
rickets in Italian: Rachitismo
rickets in Japanese: くる病
rickets in Dutch: Rachitis
rickets in Norwegian: Rakitt
rickets in Polish: Krzywica
rickets in Portuguese: Raquitismo
rickets in Russian: Рахит
rickets in Simple English: Rickets
rickets in Slovenian: Rahitis
rickets in Swedish: Rakitis
rickets in Turkish: Raşitizm
rickets in Chinese: 佝僂病

Synonyms, Antonyms and Related Words

Lombardy leprosy, anemia, ariboflavinosis, beriberi, cachexia, chlorosis, deficiency anemia, dermatitis, goiter, greensickness, keratomalacia, kwashiorkor, maidism, malnutrition, night blindness, osteomalacia, osteoporosis, pellagra, pernicious anemia, protein deficiency, rachitis, scurvy, struma, vitamin deficiency, xerophthalmia
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